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Explanation Of Gastric Emptying Procedure Using Cervical Traction
Posted by
screeb
,
10 April 2010
·
157 views
The procedure, in a nutshell, is this: for one hour after rocking on one’s sides, contactions from the proximal colon are induced (and palpable). The above steps are necessary for the cervical traction device (TD) to function. During application of TD, one lies on one’s side while performing neck pulls in order to increase external transmural pressure on the sub-occipital triangle’s muscle spindle afferents. The following analysis of the inputs of the procedure uses known research about how the steps of the procedure work.
Afferent fibers originating from skeletal muscles are activated during exercise and release substance P (SP) in to the NTS (Nucleus of the solitary tract). SP which activates NTS GABAergic (inhibitory ) neurons. The cervical traction device puts pressure on the sub-occipital muscles, which cause the muscles stretch receptors (myofibrils) to project to and activate the ImN (Intermediate Nucleus). The ImN acts to integrate information from the head and neck and relays this information on to the NTS where suitable autonomic responses can be generated. Some intracellular recordings in NTS neurons following stimulation of the InM had both GABAergic (inhibitory) and glutamatergic (excitatory) components. The existence of nitrergic InM neurons which are glutamatergic, corresponded to 45+ 11% of the VGluT2 (vesicular glutmate transporter type 2) population of neurons in the ImN. Fibers labeled for VGluT2 were in close apposition ( an excitatory configuration) to fibers and neurons labeled for the NK-1 receptor, in the NTS. Therefore, SP acting at its receptor (NK-1) is excitatory to VGluT2, (glutamatergic), therby inhibiting a GABAergic neurotransmitter projection to the NTS.
The effect of GABA in the area of the medial subnucleus of the NTS on gastric motility was studied. Intra-NTS GABAergic signaling between the vagal afferent nerve terminals and inhibitory projection neurons in the NTS that comprise the functionally relevant efferent arm of the vagovagal circuit, (the level of activity in the DMVX (dorsal motor nucleus of the vagus). The activation of DMVX causes decreased cecal contractions. however, the reduction of GABA at the NTS causes cecal distension. The cecocolonic junction (CCJ) has been suggested to by a sphincter since cecal distention effected a significant CCJ pressure reduction. The CCJ and ascending colon (AC) showed similar frequency and conduction velocity. The similarity in frequency and conduction velocity of electric waves of the CCJ and AC, denotes that the AC waves are a continuation of those of the CCJ, and that both are evoked by the same motor activity, probably located in the CCJ. This would cause a reduction of transmural pressure on a bolus through the proximal colon, reducing proximal distension that inhibits gastric emptying.
Afferent fibers originating from skeletal muscles are activated during exercise and release substance P (SP) in to the NTS (Nucleus of the solitary tract). SP which activates NTS GABAergic (inhibitory ) neurons. The cervical traction device puts pressure on the sub-occipital muscles, which cause the muscles stretch receptors (myofibrils) to project to and activate the ImN (Intermediate Nucleus). The ImN acts to integrate information from the head and neck and relays this information on to the NTS where suitable autonomic responses can be generated. Some intracellular recordings in NTS neurons following stimulation of the InM had both GABAergic (inhibitory) and glutamatergic (excitatory) components. The existence of nitrergic InM neurons which are glutamatergic, corresponded to 45+ 11% of the VGluT2 (vesicular glutmate transporter type 2) population of neurons in the ImN. Fibers labeled for VGluT2 were in close apposition ( an excitatory configuration) to fibers and neurons labeled for the NK-1 receptor, in the NTS. Therefore, SP acting at its receptor (NK-1) is excitatory to VGluT2, (glutamatergic), therby inhibiting a GABAergic neurotransmitter projection to the NTS.
The effect of GABA in the area of the medial subnucleus of the NTS on gastric motility was studied. Intra-NTS GABAergic signaling between the vagal afferent nerve terminals and inhibitory projection neurons in the NTS that comprise the functionally relevant efferent arm of the vagovagal circuit, (the level of activity in the DMVX (dorsal motor nucleus of the vagus). The activation of DMVX causes decreased cecal contractions. however, the reduction of GABA at the NTS causes cecal distension. The cecocolonic junction (CCJ) has been suggested to by a sphincter since cecal distention effected a significant CCJ pressure reduction. The CCJ and ascending colon (AC) showed similar frequency and conduction velocity. The similarity in frequency and conduction velocity of electric waves of the CCJ and AC, denotes that the AC waves are a continuation of those of the CCJ, and that both are evoked by the same motor activity, probably located in the CCJ. This would cause a reduction of transmural pressure on a bolus through the proximal colon, reducing proximal distension that inhibits gastric emptying.
