5 replies to this topic

[annie7]

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just read that prucalopride/resolor was recommended for approval in europe in july. the following is from the movetis website. link is below. if the link doesn't work just go to movetis.com and look under press releases."Turnhout, July 27, 2009 – Movetis announces today that it has received a positive opinion from the Committee for Medicinal Products for Human Use (CHMP) of the European Medicines Agency (EMEA) on the European Marketing Authorisation Application (MAA) for its lead product, prucalopride for the treatment of chronic constipation (CC)." http://www.movetis.c...authorisation-ai sure do hope it gets approval in the usa soon. think it's still in phase three. http://www.movetis.c...ic-constipation

[jkgreene1976]

just read that prucalopride/resolor was recommended for approval in europe in july. the following is from the movetis website. link is below. if the link doesn't work just go to movetis.com and look under press releases."Turnhout, July 27, 2009 – Movetis announces today that it has received a positive opinion from the Committee for Medicinal Products for Human Use (CHMP) of the European Medicines Agency (EMEA) on the European Marketing Authorisation Application (MAA) for its lead product, prucalopride for the treatment of chronic constipation (CC)." http://www.movetis.c...authorisation-ai sure do hope it gets approval in the usa soon. think it's still in phase three. http://www.movetis.c...ic-constipation

I'm in the USA and got a prescription from my doctor for resolor (had to sign a waiver due to not being FDA approved) ordered it from www.canadadrugs.com , 2mg - once daily - 28 day supply - $159 usd , just took first dose today, side effects are obvious dizzy, very mild headache, overall odd feeling, some bowel noise, occasional ill feeling in gut that seems to disapate quickly, mostly considered very common 1 in 10 , and should subside in 4-5days.

[annie7]

that's terrific that your doc wrote you a script for it! fingers crossed it works well for you. please keep us posted if you get a chance--thanks!

[jkgreene1976]

I'll just paste my rant from another topic.....OK, so I am a 25 yr old male, I started having issues 3 or 4 years ago (seems like forever) now as a kid always had large BM's, but without much issue.... in 2008 suddenly started have severe problems, felt like an impaction, after alot of laxatives things got slightly better but had developed gurd and major exsesive beltching, first doctor said it was mental. sent me for mental health treatment (yea my anxiety was high, who's wouldnt wen you feel your dieing)anyhow over the last 3-4 yrs I have had a few different diagnosis, #1 mental, #2 chronic idiopathic constipation, #3 pelvic floor dysfunction, #4 colonic inertia (slow transit constipation) have had every test and medication under the sun and beyond....besides the constipation they did find "an unusual amount of aortic calsification" but not enough to warrant treatment "yet" and 1 kidney was enlarged, they could see contrast go to it (but not in it but could see it exit)within my reg. physician and a digestive specialist at end point was only offered a eiliostomy/colostomy one or the other.being the type that feels those internal organs are there for a reason, with what research I've done I took myself to University of Washington Medical Center to get some hi-tech answer's.things I asked about: #1 interstim sacral nerv stimulation (not being performed for constipation yet, unless you pay cash in exess of $20k) #2 colonic pacing ^similar to the above but placed on the large intestine (in trials/not being performed) #3 other test's / other drugsagain it was suggested to do a eliostomy with a "maybe" regaurding removing the entire lrg intestine and having a ostomy, or a "maybe" lrg intestine removal and re-attach the sml intestine and no ostomy (or maybe a temp one)anyhow i asked if there were ANY other options, they spoke about some drugs that were not FDA aproved "yet" in their opinion the most promising was Resolor (Pruculopride)Resolor: it is aproved in some areas, but not the US and in those areas it is aproved it's not aproved for men because: in the clinical trials consisting of 2700 people most were women and it was decided there wasn't enough evidence to aprove it for men.so my UofW doctor wrote me the script after i signed a waiver as so they are at no fault if something negative happened.... ordered the resolor online (you can PM me if you want to know where) recieved it and am on day 4, day 1 about 2hrs after taking it I had a dizzy feeling and gradualy got a mild headache both persistant till bed time, the next day the dizzy sensation was still there and persistant but the headache was not, on day 3 felt great almost no dizzyness, and had 2 BM's with some straining but seemed easier, on day 4 felt fine and had 1 spontainious BM, (which was surprising because my issue has been simply no urge to go) and 1 more BM but not spontainious and with a little straining, although this eveing I am feeling the dizzyness again and just a little "out of it" we'll see what tomorrow brings.O and I'd say since day 2 my gut started and has increased in making noise (movement) and I am also hungry more often so probly a good thing.

[jkgreene1976]

so in other words I think it's working but with some side effects and we'll see how it goes as they are said to subside...... but after 3-4 yrs I'm not gonna hold my breath or have my hopes too high.

[tableandchairs]

so in other words I think it's working but with some side effects and we'll see how it goes as they are said to subside...... but after 3-4 yrs I'm not gonna hold my breath or have my hopes too high.

So how have things been since the last time you checked in? I started Resotran today and noticed I'm hungrier than usual too! Would love to hear how things are going more than 2 months into taking the medication.