Posted 16 July 2002 - 04:41 PM
My board-certified GI explained to me that IBS is a disorder of the function of the intestinal muscles, which may contract too forcefully or weakly, too slowly or rapidly in IBS patients. And when this happens, gas can get trapped.
IBS is disorder of function which produces symptoms. The mechanism by which the symptoms occur is not so easy to determine. Motility could be involved..but how and to what degree has not been determined. Most studies don't find too much difference in motility in IBS persons compared to healthy people. That is why IBS is still defined by symptoms.
That's why anti-cholinergic works so well on trapped gas
"Trapped gas" is generally not the signficant factor in IBS..the pain and bowel symptoms are.
often had excruciatingly painful periods where I would go 2-3 days without passing gas even once. And the more time that would pass without farting, the more pain I was in. The first time I ever took an
This does sound abnormal, but it's not necessarily the gas being that held that causes your discomfort, it's IBS itself.
pass are tried-and-true drugs that have been on the market and used by IBS patients for years.
Most studies have never found these drugs of much value. That is everyone has invested so much for Lotronex and Zelnorm.
At the same time, we know there are two basic contractions in the gut
I should also point out there is another aspect to motility is that is muscle tone. Increased tone (resistance to diameter increase) could hinder gas motion through the gut. Anticholiergics do reduce tone.
I am not a doctor, but utilize sources of information not readily available to the public. Some of this information may contradict what you think you know and some of it may sound harsh, but the information is what it is, and you got it here for free. I am just a messenger. Always consult a real doctor.