Posted 25 June 2007 - 10:58 AM
"I don't know of any study that Pimental did that concluded that SIBO does not cause IBS. Please advise where I can find this."Pimental didn't do the study. That Pimental Believed that SIBO caused IBS in the first place was always speculation and has never been proven to begin with. Other centers have not be able to replicate his studies. People can have SIBO and not have IBS and have IBS and sibo and some just have IBS.However this study used better testing for SIBO then the lactulose breath test.NEW YORK (Reuters Health) - An abnormally high number of bacteria in the small intestine does not appear to be a major factor affecting the symptoms of irritable bowel syndrome, Swedish researchers report in the medical journal Gut. Irritable bowel syndrome (IBS), or spastic colon, is a common disorder characterized by abdominal pain, diarrhea, cramping, and constipation. The syndrome is thought to arise from overactivity of the nerves in the intestine that control movement."The data do not support an important role for small intestinal bacterial overgrowth, according to commonly used clinical definitions, in IBS," senior investigator Dr. Magnus Simren told Reuters Health.Simren and colleagues at Sahlgrenska University Hospital, Gothenburg, note that a high rate of bacterial overgrowth has been reported in patients with IBS, but these observations were based on tests that only indirectly measured bacteria levels.They therefore assessed small intestinal bacterial overgrowth by a direct test -- bacterial culture of small-bowel test samples -- among 162 patients with IBS and 26 healthy subjects. Cultures revealed the exact same rate of intestinal bacterial overgrowth in both groups, 4 percent.Signs of intestinal movement abnormalities were seen in 86 percent of patients with overgrowth and in 39 percent of patients without overgrowth. The investigators also observed that movement abnormalities did not reliably predict altered small-bowel bacterial levels.SOURCE: Gut, June 2007.In the above study four percent of the IBSers had SIBO as well as 4 percent of the control group who didn't have IBS had sibo.
I am not a doctor. All information I present is for educational purposes only and should not be subsituted for the advise of a qualified health care provider.
Please make sure you have your symptoms diagnosed by a medical practitioner or a doctor.