Posted 09 January 2008 - 03:49 PM
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Posted 24 June 2009 - 04:07 PM
http://www.medicinen...pse/article.htmIt looks like from a couple of papers that it depends on what genes you get for connective tissues as that is what the valve is made of. It ranges in severity from people who don't notice anything to very severe as well. While sometimes a specific drug causes a specific defect but most of the time stuff like this is which genes you have and how the parts happen to grow and some people's parts get made in a way they don't have problems with them and some people have problems with any given part.
The mitral valve prolapse (MVP) syndrome has a strong hereditary tendency, although the exact cause is unknown. Affected family members are often tall, thin, with long arms and fingers, and straight backs.
Posted 25 June 2009 - 08:44 AM
Posted 25 June 2009 - 09:30 AM
Posted 21 July 2012 - 08:15 PM
If anyone had a baby with birth defects using zofran please contact me mwmexx @ gmail.com I received in the E.R. Ondansetron a serotonin 5-HT3 receptor antagonist used mainly to treat nausea and vomiting following chemotherapy and after surgery. There is little information about their effect on the pregnancy and therefore the standard advice is to avoid unless absolutely necessary. Evidence on the safety of 5HT3 inhibitors (such as ondansetron) in pregnancy is limited. I did not receive any information about this drug before using it on me, the doctor only said that it was an “unbelievable expensive antinausea medication”. Before I left the E.R. My husband questioned him about the drug. The assured him that this drug was not dangerous to my baby. I am sad because they injected me zofran without warning me about the lack of studies about the effects of this medication in pregnant women, especially in the first trimester. I am also upset because there are many mild and proven medications for treating nausea in pregnant women and they gave me a medication that is mainly prescribed for nausea and vomiting following chemotherapy and after surgery.We came to the hospital looking for relief and we trusted the doctors to make the right decisions. Some of the known side effects of Ondansetron include:· Slow heart rate (bradycardia)· Abnormal heart beats (arrhythmias)· SeizuresI did not presente any of those symptoms after the injection. However, I have no doubt that this medication affected my baby’s heart. The heart is developing its structures within the first 8 weeks and they injected me with Zofran at 7 weeks . It seems likely that a medication that has exhibited electrophysiological effects on the cardiac muscle in children and adults would affect the forming structures of my baby’s heart. My baby was born with a collection of very unusual heart problems. That unusual collection of heart defects cannot be probability only!!!!. Those problems according with medical literature are associated with an event happening in the first 8 weeks of pregnancy. Zofran was the only medication I took in my entire pregnancy. We learned about our baby’s birth heart defect at 14 weeks, and my husband and I chose to give our baby a chance at life, and not to have an abortion. I was very careful about taking care of my self throughout my pregnancy. I chose to give birth with a C-section because while this increased my risk, it lowered the risk to my child. I made many sacrifices to give my daughter her best chance at life. I would ever knowingly allow the doctors to give me this unproven medication if I had known how little was known about its effect on pregnant women. Do not allow that embryonic human life to be exposed to substances that might harm them and obstruct their normal development. Why whether this medication warns its use in children does not warn its use in pregnant women who carry little childs inside them? Why a package of cigarrets warns about its possible effects in pregnant women and an antinausea medication does not? This might not be of your concern, but my tears don't stop since then, and everytime I take my baby to the hospital. She had a heart surgery already and some more comming.
Posted 21 July 2012 - 08:37 PM
Posted 21 July 2012 - 08:41 PM
[size="3"][font="Century Gothic"]I have been pregnant three times. the first pregnancy I had morning sickness but since I was gaining weight the doctor did not give me any medicine for it. So I worship the Porcelain gods for 4 months. My son was born healthy. But my other two pregnancies I was on Zofran. Both my second son and daughter were born with a heart birth defect. My second son was born with VSD (layman's term hole in the bottom of the heart) and my daughter was born with an abnormal pulmonary value. It is crocked and "u" shaped. There has been no family history of heart birth defects on either side of the family and the doctors are not saying if there is a link. I believe ther is a link. How can one mothe who took Zofran be give birth to two children with a heart defect? i am looking for other families and mothers who have the same situation as I do to raise awareness to company that yes it does causes birth defects. I'm not in it for the money. I want to make sure other mothers do not have to go through what I go through. I have been blessed with the fact that their cardiologist is avoiding surgery and there has been some healing in their hearts. My daughter is currently not on any medication. My son is only on a diuretic. If you look at them you could never tell they have a heart defect. They have hit every milestone and act like normal.
Posted 22 July 2012 - 07:02 PM
Posted 14 August 2012 - 06:39 AM