Prescription Medications

EnteraGam™ is a prescription medical food product that has been shown in clinical studies to improve GI absorption, immune function and mucosal barrier functioning in the intestine. It acts within the GI tract, going beyond symptom management by targeting multiple factors in IBS-D. In clinical trials, it significantly reduced the number of days with GI-related symptoms; has been used safely up to one year in length; and has no restrictions on length of therapy.

LOTRONEX® is a medicine only for some women with severe chronic IBS whose main problem is diarrhea and IBS symptoms have not been helped enough by other treatments. Some patients have developed serious bowel side effects while taking lotronex.

LINZESS® (linaclotide), CONSTELLA® in Canada and Europe, is a prescription medicine approved by the FDA to treat adults with IBS-C and Chronic Idiopathic Constipation in men and women 18 years of age and older. “Idiopathic” simply means the cause of the constipation is not known and not due to an underlying illness or medication.

AMITIZA® is a prescription medicine approved by the FDA to treat adults with IBS-C and Chronic Idiopathic Constipation in women 18 years of age and older.

ZELNORM® (tegaserod) is a prokinetic agent that works by targeting the serotonin 5-HT4 receptors in the intestines. it has been approved by the FDA to treat IBS-C .

MOTEGRITY (usa) / RESOTRAN (canada)/ RESOLOR (europe, etc) (Prucalopride) Prokinetic agent that works by targeting the serotonin (5-HT4) receptors in the intestines. Used for the treatment of chronic idiopathic constipation in people for whom laxative treatment has failed to provide relief by stimulating the muscle movement.

TRULANCE (plecanatide) is a new medication approved by the FDA for chronic idiopathic constipation and IBS-C in adults.


PIZENSY (lactitol) is a new medication approved by the FDA for chronic constipation in adults

Antidepressants, Antispasmodics, Antidiarrheals:

Although antidepressants were developed to treat depression, research studies have shown that they can also be effective in reducing pain. Antidepressants are, therefore, effective in treating symptoms of IBS and other functional GI disorders. Patients who have taken antidepressants for their IBS symptoms have reported significant improvement in their abdominal pain and reduction in other IBS symptoms, such as diarrhea, constipation, bloating, nausea or urgency. Antispasmodics and Antidiarrheals are helpful in reducing periodic painful episodes of spasms and diarrhea respectively. Patients who have been taking antidepressants should be aware of the possibility of developing Antidepressant Discontinuation Syndrome, or SSRI Discontinuation Syndrome, upon rapid stopping or tapering the use of antidepressants.

Antibiotics: Bacterial overgrowth specific

While the cause of irritable bowel syndrome is uncertain, there is some research evidence suggesting that it may be caused by an abnormal growth of bacteria in the small intestine, referred to as Small Intestinal Bacterial Overgrowth (SIBO). A specific regiment of antibiotics have been investigated to treat this condition.

Fecal Microbiota Transplantation (FMT)

Fecal Microbiota Transplantation (FMT) also known as a stool transplant or simply fecal transplant is the process of transplantation of fecal bacteria from a healthy individual into a recipient. This forum is for the discussion of FMT, its use and effectiveness, in the treatment of digestive disorders.