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Mechanisms and efficacy of dietary FODMAP restriction in IBS

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#1 Jeffrey Roberts

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Posted 04 June 2014 - 09:06 AM

Mechanisms and efficacy of dietary FODMAP restriction in IBS
Heidi M. Staudacher, Peter M. Irving, Miranda C. E. Lomer and Kevin Whelan
Nature Reviews Gastroenterology & Hepatology 11, 256–266  (2014) doi:10.1038/nrgastro.2013.259 Published online 21 January 2014
IBS is a debilitating condition that markedly affects quality of life. The chronic nature, high prevalence and associated comorbidities contribute to the considerable economic burden of IBS. The pathophysiology of IBS is not completely understood and evidence to guide management is variable. Interest  in dietary intervention continues to grow rapidly. Ileostomy and MRI studies have demonstrated that some  fermentable carbohydrates increase ileal luminal water content and breath hydrogen testing studies have  demonstrated that some carbohydrates also increase colonic hydrogen production. The effects of fermentable carbohydrates on gastrointestinal symptoms have also been well described in blinded, controlled trials. Dietary restriction of fermentable carbohydrates (popularly termed the ‘low FODMAP diet’) has received considerable attention. An emerging body of research now demonstrates the efficacy of fermentable carbohydrate restriction in IBS; however, limitations still exist with this approach owing to a limited number of randomized trials, in part due to the fundamental difficulty of placebo control in dietary trials. Evidence also indicates that the diet can influence the gut microbiota and nutrient intake. Fermentable carbohydrate restriction in people with IBS is promising, but the effects on gastrointestinal health require further investigation.
© 2014 Macmillan Publishers Limited. All Rights Reserved.

  • annie7 likes this

#2 annie7


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Posted 18 July 2014 - 03:28 PM

thanks for posting this, Jeff.  i just read this study on the IBS Reporter Newsfeed. 


thanks for providing the link to the entire research paper. i do hope they investigate all this further. i've been on a low FODMAP diet for several years now, ever since i first read about it here on the board and i've been wondering about possible long term effects of it.


and they're right about the importance of consulting a registered dietician when following this or any restrictive diet.

these are just my own thoughts. for expert medical advice please contact a health care professional.

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