Link between SIBO and fibromialgia (study) - Fibromyalgia (FMS) and Chronic Fatigue Syndrome (CFS) - IBS Self Help and Support Group Forums -

Jump to content


Link between SIBO and fibromialgia (study)

sibo fibromalgia study

  • Please log in to reply
1 reply to this topic

#1 vanessa6801


    Regular Member

  • Members
  • PipPip
  • 73 posts
  • Country:Brazil

Posted 16 December 2014 - 03:58 AM

I came across this article and I thought I might post it here. I do not suffer from fibromalgia myself but ongoing fatigue is one of the symptoms that ive had since ive developed ibs and im quite certain that there is a strong link between the 2.
One of the authors of this study is mark pimentel, author of 'new ibs solution'.
Link to article (full article is available as pdf) http://www.ncbi.nlm....les/PMC1754959/

A link between irritable bowel syndrome and fibromyalgia may be related to findings on lactulose breath testing

M Pimentel, D Wallace, D Hallegua, E Chow, Y Kong, S Park, and H Lin

Author information ► Copyright and License information ►

This article has been cited by other articles in PMC.


Objective: To compare the prevalence and test results for bacterial overgrowth between IBS and fibromyalgia.

Methods: Subjects with independent fibromyalgia and IBS were compared with controls in a double blind study. Participants completed a questionnaire, and a lactulose hydrogen breath test was used to determine the presence of SIBO. The prevalence of an abnormal breath test was compared between study participants. Hydrogen production on the breath test was compared between subjects with IBS and fibromyalgia. The somatic pain visual analogue score of subjects with fibromyalgia was compared with their degree of hydrogen production.

Results: 3/15 (20%) controls had an abnormal breath test compared with 93/111 (84%) subjects with IBS (p<0.01) and 42/42 (100%) with fibromyalgia (p<0.0001 vcontrols, p<0.05 v IBS). Subjects with fibromyalgia had higher hydrogen profiles (p<0.01), peak hydrogen (p<0.0001), and area under the curve (p<0.01) than subjects with IBS. This was not dependent on the higher prevalence of an abnormal breath test. The degree of somatic pain in fibromyalgia correlated significantly with the hydrogen level seen on the breath test (r= 0.42, p<0.01).

Conclusions: An abnormal lactulose breath test is more common in fibromyalgia than IBS. In contrast with IBS, the degree of abnormality on breath test is greater in subjects with fibromyalgia and correlates with somatic pain.
  • Rowe2 and jaumeb like this

#2 Rowe2


    Very Prolific Member

  • Members
  • PipPipPipPip
  • 1769 posts
  • Country:United States

Posted 10 January 2016 - 10:55 PM

This makes so much sense! Thanks for sharing!

  • jaumeb likes this

Also tagged with one or more of these keywords: sibo, fibromalgia, study


About Us | Contact Us | Advertise With Us | Disclaimer | Terms of Service | Crisis Resources

Irritable Bowel Syndrome |  Inflammatory Bowel Disease |  Crohn's Disease |  Ulcerative Colitis |  Fibromyalgia |  GERD - Reflux Disease

©Copyright 1995-2016 IBS Self Help and Support Group All rights reserved

This website is certified by Health On the Net Foundation. Click to verify. We comply with the HONcode standard for trustworthy health information: verify here