This is awesome! Wow! In a short amount of time we should have three new drugs available for IBS-C and CIC (Tenapanor, Prucalopride, and Zelnorm). I'm glad that the market is finally responding to this problem with lots of different options!
Here's a link on Tenapanor:
I have my eye on two other drugs on the horizon as well, Velusetrag and SYN-10.
Velusetrag is a drug like Prucalopride and Zelnorm, and has shown promising results for gastroperisis and constipation:
SYN-010 targets methane producing bacteria in the gut, preventing them from creating methane which is apparently a cause for slow intestinal transit and chronic constipation. It's currently going through a phase 2B clinical study at Cedars-Sinai Medical Center:
It's probably going to be some time before these make it in but hopefully within the next 5 years.