IBS-C - Linzess + Dicyclomine and motilityLinzess
Posted 21 December 2015 - 05:54 PM
I'm 66 and have suffered CIC for 45 years, which seemed to evolve into IBS-C over the past several years. About a year ago, I had a right hemi-colectomy that resulted from a cecal volvulous. I recovered quickly and quite well. I'm very active and in good health, and eat the same way, with a lot of fiber. I had been taking Miralax daily for the past two years, but it seemed to lose its effect during the past four months. It did however, kept my stools soft. I had a BM daily, but didn't empty myself on most days. I suffered extreme gas and felt an urge to go without results. The GI's nurse practitioner was going to have me take Miralax twice a day, but suggested Linzess 145 mcg. instead. I'm into my third week, though I had a colonoscopy in the second week, which skewed things. The nurse said that I could take Miralax with the Linzess, just to see how I adjust overall. The Miralax + Linzess proved to be a little too much, though Linzess, alone, also keeps things on the little-too-loose side thus far. Maybe I need to give it more time, and the nurse did suggest 90 days.
I basically suffer from dysmotility. I had a sitz marker test recently, but only three of the markers remained after the week, which is good. I was concerned that I had a stricture as a result of the surgery, so I had a colonoscopy. The GI removed three pre-cancerous polyps. However, my colon still is redundant, and my prep was inadequate for the GI to get a complete view. So, I'm going to have another colonoscopy in June, with a two-day prep (that's got to be torturous)! Anyway, as i still have some IBS symptoms with the Linzess, the nurse gave me some Dicyclomine. I read that it can slow down motility and cause constipation. It seems to me that taking Dicyclomine with Linzess is counter productive. I can live without the Dicyclomine, as I don't have the IBS symptoms every day, especially when the Linzess cleans me out. I reviewed many of the Linzess threads and found them helpful. We're all different, so our results will vary from person to person. I did find that taking Linzess with a full glass of water made it work better. I'll welcome any advice! Thanks.
Posted 01 January 2016 - 10:49 PM