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Amitryptaline for ibs - high dosage

ibsc ibsd antidepressent

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#1 LucyM1991

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Posted 01 June 2016 - 09:01 AM

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Good afternoon

 

after struggling with severe ibs symptoms for the last 9 months i was put on amitryptaline by my doctor and have been raising the dosage

since then. initially i had a good improvement, no trapped gas pains when waking in the morning, and not such an urgency for bm, and not as frequent either. i had days when my stomach felt well, which i have not had for months.

 

However, when i read up on other ibs sufferers taking amitryptaline, i see that many are using dose of 10mg or 25 mg, whilst i am on 75mg as 25mg at night did not work 

 

Has anyone else had experience of taking a higher dose of amitryptaline for ibs and has anyone had success long term?

 

any experience would be appreciated

 

Lucy



#2 lithium

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Posted 01 June 2016 - 11:28 AM

The higher the dose of amitriptyline the more its antidepressant action comes into play. Perhaps you are feeling better because of the antidepressant action? IBS also has a very big psychological component to it.



#3 pip x

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Posted 15 July 2016 - 05:46 PM

Good afternoon
 
after struggling with severe ibs symptoms for the last 9 months i was put on amitryptaline by my doctor and have been raising the dosage
since then. initially i had a good improvement, no trapped gas pains when waking in the morning, and not such an urgency for bm, and not as frequent either. i had days when my stomach felt well, which i have not had for months.
 
However, when i read up on other ibs sufferers taking amitryptaline, i see that many are using dose of 10mg or 25 mg, whilst i am on 75mg as 25mg at night did not work 
 
Has anyone else had experience of taking a higher dose of amitryptaline for ibs and has anyone had success long term?
 
any experience would be appreciated
 
Lucy



#4 pip x

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Posted 15 July 2016 - 06:07 PM

Hi Lucy. I've been on 50mg of amitriptyline for past 6 years for my ibs-a. The d was getting so bad with practically no warning I was afraid to go out. It does take a good few weeks to really get the benefits of it and you need to work up slowly. Be warned though you may suffer from severe constipation. I live on lactulose and the occasional sennokot these days.





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