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Post Infectious IBS

After acute bacterial gastroenteritis, up to one‐third of patients will have prolonged gastrointestinal complaints, and a portion of those affected will meet the diagnostic criteria for post infectious Irritable Bowel Syndrome (IBS-PI). After resolution of the acute infection, patients with post infectious Irritable Bowel Syndrome appear to have altered motility that can lead to persistent intestinal symptoms. Both bacteria type and toxins related to the bacteria as well as preexisting psychological disorders, and duration of initial infection, have been associated with an increased risk for the development of post infectious Irritable Bowel Syndrome. Current treatments for post infectious Irritable Bowel Syndrome are typically targeted at specific symptoms, although studies evaluating therapies directed at preventing or reducing the duration of the initial infection are ongoing.

Patients whose IBS is post infectious have a more optimistic prognosis than those for whom the origin of the IBS is unknown, as it is estimated that approximately half of all IBS-PI patients will return to a state of healthy digestive functioning.

DuPont Clin Infectious Diseases 2008;46:594–599 Bowel Syndrome,