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  1. General Discussion
    Some amazing research has just been published that shows neuromodulating drugs like fluoxetine, escitalopram, lithium, valproate and aripiprazole affect the microbiome and gut permeability, at least in rats/in vitro. Differential effects of psychotropic drugs on microbiome composition and...
  2. IBS Diarrhea (IBS-D)
    I've been suffering from chronic diarrhea for over a decade now. Every test I've ever taken has come back negative...but I have all the symptoms of Crohn's Disease or some form of IBD. Of course every gastro doctor I see has a different opinion. Some say yes, its Crohns, others say no...its just...
  3. General Discussion
    Hey, I'm planning to trial many of the wonderful AD's, antidepressants, for constant pain as well as continuous tension headache. This process may take a year or longer considering that each trial needs to last 1-3 months. I'm not sure who would be the best doc for this, GP or GI or...
  4. Your Story
    Hi guys, I have been diagnosed IBS-D for about 10 years and I took Paroxetine 20mg/day for 5 years. It's been miraculous for me as I could do whatever I wanted during the 5 years (travelling, studying, working) without ANY symptoms but the side effects. Now the paroxetine doesn't work anymore...
  5. IBS Diarrhea (IBS-D)
    Hello! My doctor just prescribed me Librax today for my IBS-D symptoms, and while I am quite excited to try it out, I am worried with the long list of interactions. Mainly, those concerning alcohol, caffeine, and Imodium. It says to avoid or try to limit the usage of these things when taking...
  6. Your Story
    Hi I have been suffering with IBS since i was 15. Was in a very bad way until i started low FODMAP. That has significantly improved my life, stopping sickness and diarrhea. But i still get cramps. Was given mebeverine that blocked me up and made me worse. Doc has just given me amitriptyline. I...
  7. IBS Diarrhea (IBS-D)
    I wanted to share what helped my IBS-D. After dealing with episodes of extreme pain and diarrhea every couple weeks for months, I was referred to a really good gastrointerologist. After trying all the conventional treatments (fiber, probiotics, etc) he finally put me on an ultra low dose of a...
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