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Researchers have conducted a head-to-head review of the effectiveness of two types of laxatives, lactulose and polyethylene glycol (PEG) (Miralax). These products are both osmotic laxatives, which work by increasing the amount of water secreted by the intestines. Both products have research support in terms of their effectiveness and safety. PEG is available over the counter, while lactulose requires a prescription.

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