This does indeed intrigue me.* Depression* Attention deficit hyperactivity disorder* Bulimia nervosa* Generalized anxiety disorder* Panic disorder* Obsessive-compulsive disorder* Posttraumatic stress disorder* Social phobia* Dysthymic disorder* Migraine* Irritable bowel syndrome* Fibromyalgia * Cataplexy* Narcolepsy* Premenstrual dysphoric disorderI have been diagnosed with 10 of the above.A common successful treatment protocol isn't all that links the conditions. Researchers have also found that they run in families andthat several conditions often occur in the same people. The commonalities have led to the group of conditions being lumped under the name "affectivespectrum disorder".Can I relate to the above or what?!!Background Affective spectrum disorder ASD represents a group of psychiatric and medical conditions, each known to respond to several chemical families of antidepressant medications and hence possibly linked by common heritable abnormalities. Forms of ASD include major depressive disorder MDD, attention-deficit/hyperactivity disorder, bulimia nervosa, cataplexy, dysthymic disorder, fibromyalgia, generalized anxiety disorder, irritable bowel syndrome, migraine, obsessive-compulsive disorder, panic disorder, posttraumatic stress disorder, premenstrual dysphoric disorder, and social phobia. Two predictions of the ASD hypothesis were tested: that ASD, taken as a single entity, would aggregate in families and that MDD would coaggregate with other forms of ASD in familiesThis information is extremely relavent.It is important to be able to link behavioral health disorders with functional dysorders such as IBS with respect to approaching treatment, don't you think?Ok... so now that we know these disorders are linked, and that antidepressants can help, can we identify a root cause or a potential "cure"?? I ask because I prefer to treat causes instead of symptoms when possible.Evie