Please excuse my rather graphic screen name, but honestly its how I feel...like I have a gutterbutt. I have IBS-D and have had it since I was 18 years old. It has progressively gotten worse as I have gotten older, either that or I just don't handle it as well as I use to. I was reading all different spots on this site and came across a suggestion of taking this probiotic called Align. I am wondering if anyone out there has tried it and what their experience is. Currently, I take Sertraline daily, and 1/2 of an Immodium every day to every other day, I also take Peppermint Oil/Ginger/Fennel capulates as needed (which is often). I am trying to find a balance as things have been getting unbearable again. At one point my doctor had me on like seven different medications to combat this and I received no relief. On my own I cut back to the Sertraline as the only prescribed med. Things have gotten so bad that my job could be in jeopardy, like I need more stress in life, so am wondering if this Align is worth trying or not. I am so tried of spending tons of money to try things that never seem to help or seem to make things worse.