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Allegra (fexofenadine hydrochloride) has been shown in some research studies to reduce D and normalize stool consistency. There is some evidence that IBS sufferers may have too much histamine. Allegra is referred to as a 2nd and 3rd generation antihistamine. The usual side effects from antihistmines, dry mouth and sleepiness, are not present.

I was encouraged by this person's story with Allegra, albeit he has colitis vs. IBS; http://www.ihaveuc.com/toms-success-against-colitis-with-fexofenadine/

This person who has IBS posted an encouraging note; http://www.ibsgroup.org/forums/topic/88057-allegra/

I thought I would give Allegra a try.

I took 120 mg (24 hour dose) with breakfast.

Within 30 minutes I had very dramatic left side cramping, followed by multiple bowel movements. After 3 hours, the bowel movements have continued, albeit the cramping has subsided.

Allegra for me at this strength actually makes things worse.
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Maybe IBS-C sufferers can benefit from this?

Jeff
 

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Interesting. I recently switched from Loratadine to Allegra because Loratadine is packaged with Lactose and I need to take something for my allergies. I'll have to check my food log when I get home, but I wonder if the Allegra has been partially responsibly for my recent flare-ups.
 
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