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Discussion Starter · #1 ·
I guess it's just like Zelnorm for me...the Amitiza worked in the beginning, but now it's lost its efficacy. At first, I didn't even have to take it everyday. Now I do take it everyday, and I haven't gone to the bathroom for about five days.Did this happen to anyone else?
 

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I've been on Zelnorm for over 2 1/2 years and the last few weeks it does not seem nearly as effective. I guess I should feel lucky as many poeople have complained it hasn't worked at all for them. I'm going to get some Pericolace, a rather mild laxative, and take it for a few days to take a break from the Zelnorm. I've read where some take Zelnorm or amitza every other day just to keep it working.Maybe your body needs a break from it. I dont know I'm frustrated myself right now.
 
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