I don't know if you've had your trip yet or not. Not sure how many hours ahead of EST you are!Yes take some immodium, and you can take it on an empty stomach. How much to take depends on how bad your D is and how much it usually takes to stop it. If my stomach is essentially empty and i'm feeling those twinges, i take 1/2 an immodium. if it continues, i take another.I doubt probiotics could help you in time for your trip. That is more to achieve overall healthy intestinal flora and it's not going to happen overnight.Please, everyone, take some of osumex's statements with a grain of salt. He may be just trying to help, but he does sell probiotics and has posted nearly identical messages on many posts.Good luck, saffie! I bet you'll be FINE!! And the more you tell yourself that, the more likely you will be. The more you worry about D, the more likely it will happen.