i have written about histamine in other posts, here............it may b that by counter-acting the histamine ur stomach is producing, it may help to stop subsequent production of gastrin & others..........but it is only a stop gap.........the over production of histamine is ur stomach' way of trying to get the production of hydrochloric acid stepped up..........when all is in the proper amounts, there is a feed-back that stops the excess histamine..........when things like this happen, it usually cause there's something screwy in denmark...........some part of the production of digestive juices & subsequent hormones is not working properly...........taking some drug to stop or counter-act any part of the process, doesn't really cure anything..........i've been dealing with health issues for many yrs & it has been my experience, that if u only treat various parts of the cascade of things our bodies do to try to fix things, then somewhere along the line, something else will take the place of what u r dealing with now..........& when that happens, the thing that takes it's place, is usually worse than the other thing i dealt with........it can take yrs or even decades to happen...........our bodies will go a long way to get our attention.........& we can ignore it to our detriment!!!!