I've been using Robinol Forte since January with good results. If I'd never had Lotronex to compare it to, I would say with great results. Anyway, it really "firmed" things up and I've really had very few bad days (compared to life before Lotronex). The downside to Robinol for me is having to take it 4 times a day which means I have to carry it with me everywhere I go. I have it in the car, my purse, etc. But at least I feel free to go places. If I know I'll be in a possible stressful situation, or if I'm the least bit unsure, I take an Imodium before I leave home just to be on the safe side.I also started calcium 3 times a day last week. So far so good. When I get brave enough, I'm going to skip some Robinol and try just the calcium.