I have never tried it. I am a nurse and give it to many of my patients for depression and sleep issues. I am REALLY curious how this works for you so please keep us posted !!! What dose are you taking by the way ??One of the side effects tends to be "drying out" so can cause constipation which can help alleviate the diarrhea symptoms. I am seriously considering taking a TCA antidepressant. Only problem for me is that I dont' want to gain weight because I am already over weight.