For several years I have been suffering from severe IBS both C and D. Laid up on the weekends, no energy. Went to the doctor and he put me on the same reg, antispasmodics, antianxiety and antidepression. After 1 year of his bull****, I finally decided to try methadone. This is available to me from my roommate who suffers from chronic pain. As Bkitts posted on 10-1-03, even though the person suffered from fibro she reported relief from IBS as well. I can tell you that I take 10 mg in the AM and it usually last for 24 hours, I have normal bowel movements and bloating is a thing of the past. I'm not worried about tolerance because methadone has been studied for over 60 years and you really don't build up one like you do with vicodin. I tried vicodin and norco, with only temporary relief. I'm telling all of you, you want out of your hell, scream at your doctor for a prescription of methadone. For some strange reason (one that needs study) it corrects the colon operation and no I don't get constipated. I have normal BM now and my roommate is gracious enough to keep a steady supply of the drug for me (for free, he really saw the torture I was going through). I've been down the bentyl, librax, gas-x, high fiber, bull**** road and methadone was like a miracle drug. The only screwed up thing is that it's a schedule II narcotic, but there is no "high" associated with it. I operate more normal now than I did before with the different "antispasmodic" bs. I'd say go to your doctor right now, scream for a methadone prescription and see what happens.Yeah, yeah, methadone is for herion addicts but now a days they are actually finding different uses for it. It's highly effective in pain management and soon they will probably discover that it promotes proper bowel regulation for those who suffer from IBS. Just give it a shot, print this out and take it to your doctor. Just ask him or her, what do we have to lose?Cheers! An ex-IBSer!