I don't think they are really connected with IBS, but I've had problems around my rectum area ever since I got IBS. Fissures, hemmies, and I got my first boil down there a month ago. I think it has a lot to do with straining, sitting so long on the toliet, wiping so much. Not 100% about that with the boils, since I've only had one. But I know they are just SO horrible. Mine is still healing, and is still sore and it broke open over a month ago. I hope to never get one again!Jennifer