when i took anti-inflammatory drug many years ago i had my first attack.Lower bowel bar who send me to the E.R.I'm still irritated in the area belowthe navel and each sides.Gas and spasms and somekind of constipation are the 247 activity in the area.It is near the bladder and totally related to ibs.Don't try to obstinate me,the bladder is 100% link to the bowel.Somedays they will show you.