Hi Julee,I am IBS-C so I know what it is like to go days without. I find that Perdiem helps as far as that goes and it kicks in within 12 hours, so i take it at like 6 at night so it will kick in at 6 in the morning (before I have to go anywhere). I've gone up to three weeks without being able to, so I feel your pain about having to but not being able to. For me the full teaspoon is too much (gives me D). I have to take 1/2 tsp. and it is a litle less than I need but I don't have to worry about getting D. Then perhaps resume the citrucel.Good Luck,Kari