My doctor put me on estradiol tablets, 1.5 mg to try to resolve two large cysts on my left ovary, and 4 small one on my right. I have taken them for about a month, and will go back to the doctor for another ultra sound on the 22nd of this month to see how things are going. My question is...can HRT make you a crazy person? When I first started taking them, I felt great, or maybe I just thought I did? Now everything sets me off. I am overly emotional. Either a commerical can make me cry, or I am a complete ######! I had to refill my prescription, (Doc gave me the first 30 days, and wrote the script so it could be filed at the pharmacy to fill when the other ran out) and they told me that it was not 1.5 mg.'s it is 1. Will the fact that it is a lower dosage help?