Hi Jennifer - I can tell you that there have been a ton of posts here about people being worried of driving in a car. So, the good news is that you're definitely NOT the only one - not by a long shot! For years I also used to obsess about car rides, even short ones, although riding with somebody else in the car was so terrifying that I usually insisted on driving alone wherever I went. In my case, worrying about having an attack only increased the chances of having an attack.Antidepressants might help, but if you're looking to get some control over your worry and anxiety (which can definitely make trigger IBS symptoms or make them worse), you might also want to ask your doctor about anti-anxiety medications like Xanax or Klonopin, or even explore treatments like hypnotherapy or cognitive-behavioral therapy. Even though they all work differently, they can be extremely effective in helping you manage your obsessive thoughts. Good luck!Tim