After my gall bladder started going bad on me I would get occasional bouts of D and over the years it increasingly got worse. After the removal of my gall blader it got so it was dibilitating. I became almost a shut in for fear of going all over myself in public ( which happened to me ) For a period of about 5 years I remained indoors due to this horrible problem.I suffered from clinical depression because of this as I'd always been very active and busy, now self-confined to my home I grew almost suicidal but thankfully overcame this.My GP tried lots of different things tring to control it but nothing worked. He finally gave me a perscription for Cholestyramine (this is an old drug used at first to lower cholestrol) when I went to fill this, they didnt have the powder only the pills so desperately I got them instead .. they didnt work at all. Several months maybe a year went by and I went back to him again, he asked me to try the powder this time. I got the powder and at first started with 1 scoop twice a day in water. I saw almost immediate relief.After being on this medication for over 2 years now, my D has been controled and I am down to one scoop of powder once a day and RARELY have D.I still have to watch my oil intake as that does me a job, but all in all I'm 98% well. I hope that if you havent tried this medication that you speak to your Dr. about it and try it. Nothing ventured.