There is a new study in Sacramento for predominantly C IBS in females. I haven't heard of this drug have you? The description says it blocks the hormone CCK. I am currently taking Zelmac and suppose I should inform them of this when I go in for an appt on Tues. I'll quit taking it till then. Do you think this works like Zelmac? I'm a little sceptical about studies unless I've heard something about it. They are currently in Phase5. Any information you could help me with would be appreciated. By the way, since taking Zelmac the C is gone but the tightness and spasms remain. Please let me know what you can find out.Thanks