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The mechanism appears to be different.One thing to remember about the Enteric Nervous System (the nerves that control digestion) is that it is a complex and vast neural net. I suspect that means there would be multiple targets for altering it and relieving IBS symptoms. And that for some people some targets will work better than others.I would tell them about the Zelmac when you go in, they usually do want to know all medication you currently take.
 
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