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Discussion Starter · #1 ·
I had taken Lotronex for 3 months before I landed in the hospital with a ruptured colon and a temporary colostomy. Has anyone else experienced this? I believe there is a connection between the medication and the rupture.
 
G

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Discussion Starter · #4 ·
The doctor said it was diverticulitis. It was such a rushed surgery that he did not make a correlation between the medicine and the rupture. When I saw that Lotronex was banned, I made the correlation.
 

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Mark, I also have diverticulosis, and the colon rupturing is always something to worry about, which is why when it acts up they tell you to take care of it right away. Unless you were extremely constipated with the Lotronex, which could affect the diverticuli, it most likely wasn't caused by the Lotronex.If your doctor already knew you had diverticulosis, then he is at fault, because from what I've read the doctors are told not to give it to patients with diverticulosis as we are supposed to take care not to get constipated.JeanG
 

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Hi Mark:You've probably done tons of reading on diverticulosis. I know I have since being diagnosed with it, and mine is acting up a little now so it's on my mind. But here's an article from Jackson Gastroenterology in case you haven't seen this one.URL: http://www.gicare.com/pated/ecdgs02.htm Diverticulosis & Diverticulitis To understand diverticulosis, it is helpful to know about the anatomy and function of the intestine. The small intestine is the long, thin segment of bowel that begins at the stomach and ends at the large intestine or colon. The colon starts in the right lower abdomen and forms a large question mark across the entire abdomen ending in the rectum. Just above the rectum is the sigmoid (S-shaped) part of the colon. Liquid stool enters the right colon and, as it moves through the colon, is dehydrated so that a formed stool eventually enters the rectum. The Sigmoid Colon The sigmoid colon has the specialized job of contracting vigorously to maintain a high pressure. This action regulates the movement of stool into the rectum. And since the sigmoid is a high pressure part of the colon, it is here that most diverticuli occur. Diverticulosis Diverticulosis means that there are pockets or projections extending out from the colon. These occur very gradually over a long period of time. They occur at weak points in the bowel wall. The pockets develop because of the pressure exerted within by the contracting colon. As noted earlier, since the sigmoid colon has the highest pressure in the colon, it is here that most diverticuli occur. Because of these balloon-like projections, the sigmoid often becomes thickened and narrowed. When this happens, significant changes in the bowel function can occur, such as discomfort, diarrhea, and/or constipation. Who Gets Diverticulosis? Since it takes so long to develop, diverticulosis usually appears later in life. However, it is not uncommon to see this occur in people who are in their 30s. Eventually the colon, especially the sigmoid colon, becomes studded with these pockets. The disorder is mostly one of Western society. It is uncommon in rural Africa and India. The diet in these areas consists of unprocessed foods and grains with a very high fiber content. So, increased fiber ingestion may have great benefit. Symtoms of Diverticulosis As diverticuli form, few symptoms are noticeable, except perhaps for intermittent spastic discomfort in the left lower abdomen. Usually, there are no symptoms at all. When diverticulosis is far advanced, the lower colon may become very fixed, distorted, and even narrowed. When this occurs, there may be thin or pellet-shaped stools, constipation, and an occasional rush of diarrhea. The problem then becomes a mechanical or structural one, and treatment is more difficult. Complications of Diverticulosis It is, perhaps, remarkable that so few people have complications of diverticulosis when compared with the number of people who have the condition. Still, complications do occur and they can be serious. Diverticulitis is the most common. Diverticulitis Like a balloon, as a diverticulum expands, it develops a thin wall compared with the rest of the colon. The colon is home to many beneficial bacteria -- helpful as long as they stay in the colon. However, these bacteria can seep through the thin wall of diverticuli and cause infection. This infection around diverticuli is called diverticulitis. It can be mild with only slight discomfort in the left lower abdomen. Or it can be quite extreme with severe tenderness and fever. Treatment is usually needed for diverticulitis. It requires antibiotics and resting of the bowel by avoiding food or, at times, even liquids. For severe cases, the patient must be hospitalized. Bleeding At times, bleeding can occur from a ruptured blood vessel in diverticuli. This may produce a gush of blood from the rectum or, occasionally, black stools when the bleeding is from a diverticulum in the right colon. Perforation This complication is the most uncommon but the most serious. Bacteria escape into the abdomen where peritonitis, or an abscess, can develop. Abdominal surgery usually is required to correct this problem. Diagnosis of Diverticulitis The medical history is the physician's most important tool in diagnosing diverticulitis. The physical exam may find tenderness present in the left lower abdomen. A barium enema x-ray usually is required to determine the extent of the disorder. Flexible sigmoidoscopy and colonoscopy are exams performed through the rectum with a lighted, flexible endoscope. These exams view the colon from inside and provide additional information about the problem. Treatment of Diverticulosis Diverticulosis may be preventable. As noted, fiber, bran and roughage should be an important part of the diet. Certain types of fiber, such as wheat bran retain large quantities of water. This, in turn, provides a bulkier stool. This type of large, soft stool may help decrease the pressure in the bowel over time. Bulking agents are available in drug stores and can be effective. The generic names for some of these products are psyllium and methycellulose. Bran and fiber can be found in very palatable forms in many cereals, breads and other foods. Generally, a daily intake of 20 to 30 grams is recommended, beginning at a young age. It is known that emotional stress can increase spasms of the colon and, perhaps, result in the formation of diverticuli. Stress should be controlled and treated if necessary. Also, medications can be used to decrease spasm in the colon. Surgery may be needed to remove the diseased portion of the colon when diverticulitis occurs at an early age or when there are recurrent episodes. When surgery is done in a non- emergency situation, a colostomy is usually not needed. Summary Diverticulosis is a disorder that may be preventable if treated early in life. At any stage, there is usually effective therapy available. Diverticulitis, a complication of diverticulosis, can be readily diagnosed by the physican and effective therapy is available. Working with the physician, prevention and treatment programs can be structured to obtain the best results for the patient.
 

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Mark: Had there been any previous work done to make the diagnosis of diverticulitis? A BE or colonoscopy? I would assume that there would have been SOME symptoms of it before the actual rupture.. And if there HADN'T been a colonoscopy or something which indicated diverticulitis, what on Earth was the doctor thinking when he gave you a drug when he didn't know what he was dealing with? Something really fishy there bordering on malpractice.
 
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Discussion Starter · #8 ·
Jean, thanks for the article. Bungled, there was no colonoscopy or other test, just a doctor saying "try this". I'm sure once I have the next surgery there will be a colonoscopy to see if I have any other diverticuli.Thanks for your comments in this situation.
 
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