Missycat made a good point that the FDA cannot withdraw a product from the market - the pharmaceutical co.voluntarily withdraws it. The pharmacist at Glaxo told me that had they not withdrawn Lotronex, the FDA would have taken it to the next legal step - so basically, if the FDA "recommends a withdrawal" - it's withdrawn.Missycat also has a very good post toward the end of page 2 of Jeff's big post.From my conversations today, the FDA and Glaxo are making exactly the same claims - they each proposed compromises to restrict access to the drug, certify doctors and pharmacists, etc etc - and that the restrictions were too strict/lenient (depending on which one) to make it work. So.... we get screwed. Bottom line is that the millions that Glaxo has invested in research, development, clinical trials, distribution, & education ON TOP OF the refunds to patients they are now being forced to give - couldn't be that easy to walk away from. Even if profits are not and will not be huge, it is better than no revenue at all from such a huge 'upfront' investment.Yes, they can take the research that was the basis for Lotronex and re-configure it into new and possibly less dangerous drugs, but be realistic - by time that gets through the FDA, it will literally be years!I CAN'T GO THAT LONG WITHOUT LOTRONEX!!PLEASE BOMBARD THE FDA WITH YOUR 'TRUE LIFE' STORIES OF LIVING WITH IBS!!! I know it's a long shot, but something has to make them understand the consequences of this action!