I can really relate to the constant, stabbing, wake you up in the middle of the night, never goes away, driving you insane - abdominal pain. Zelnorm was my miracle med, but that is no longer available (thank you very much FDA*&%$*&^&)My doctor had tried me on a couple anxiety/depression meds over the years, buspar, wellbutrin, Lexapro plus antispasmodics, levbid, levsin, bentyl ...these did not help. But currently I'm taking a low dose of doxepin (50 mg in the evening) and that has greatly helped with my abdominal pain! I truly never would have believed it, but I was at the end of my rope when I tried it. Doxepin is a tricyclic antidepressant. There have been several studies showing that TCAs can help with the type of pain we are experiencing. And it is amazing how much easier it is to function (and not be anxious and depressed) when you are not in constant pain.I also follow my own very strict diet, avoid my triggers, take digestive enzymes for bloating/distention/gas, drink plenty of water and exercise. It is a lot of work to stay ahead of IBS. But maybe a TCA would help you with the pain. I know that I HATE taking any "psych" related meds, as in "this is not in my head" and I should be able to control this myself! But low dose TCAs have been proven to help with pain and that is why I'm taking it. Just so you know, my GI had thrown up his arms and gave me zero options, stating that I knew more about IBS then he did. It was my Primary's Physician Assistant who came up with the option to try low dose doxepin. I've been taking it for over 2 years now. I took a break from the med to see how I would do, but the pain returned and I went back on doxepin.Here is an exerpt from an interesting
study:http://www.ncbi.nlm.nih.gov/pubmed/19340896 (click on FULL-TEXT ONLINE is upper right corner or try this link)http://www.ncbi.nlm.nih.gov/pmc/articles/PMC2669938/?tool=pubmedEfficacy of tricyclic antidepressants in irritable bowel syndrome: A meta-analysisTCAs exhibit clinically and statistically significant control of IBS symptoms; however, given their abundant side effects they should be reserved for moderate to severe cases. Subjects should be started on subtherapeutic doses for depression and choice of drug should be tailored for each individual. We suggest using TCAs with the least anticholinergic effects (i.e. doxepin and desipramine) for elderly patients or constipation-predominant IBS and imipramine or amitriptyline for diarrhea-predominant IBS and patients with insomnia.And here is another article from
GUT:Antidepressants for irritable bowel
syndromehttp://www.ncbi.nlm.nih.gov/pmc/articles/PMC1773590/I hope this helps in someway. And yes a symptom of IBS can be constant pain, with out this med I would have constant stabbing/radiating abdominal pain due to IBS. If a doctor ever says to you it is "just IBS", then they haven't lived with it day in and day out.Hang in there, I hope you find some relief soon.Zanne