Hi mcr525. I'm sorry you are not doing that well. Certainly some of your symptoms could be IBS related. IBS is more specifically defined by pain or discomfort that is stopped when you go the bathroom -- usually accompanied by either diarrhea, constipation, or both.Thus, the stomach symptoms you describe could be IBS. However, back pain or pains in your legs is really nothing to do with IBS. I don't know anyone else on this board who has such symptoms. IBS is a gastrointestinal disorder and thus all the pains and discomforts center around your gastrointestinal track. I guess colofac is an anti-spasmatic like bentyl, levsin, nulev, etc. There are tons of things that can also produce the gastrointestinal symptoms you describe. Its important that your doctor rule all those out. The simplest are things like lactose intolerance or other food intolerance. There are more complicated things as well, though, that you should be checked for. I'm assuming your doctor determined it wasn't cancer by taking a biopsy -- he probably did a colonscopy while taking that? If so, I'm sure he checked for things such as colitis. The pain in legs and back could be anything -- including just simple back and leg pain due to joint soreness, bad posture, etc. I do know problems with kidneys can lead to pain in your back also, but I'm sure your doctor is testing all available avenues. I'd continue to work with him. You might also try changing around your diet to see if that helps. Keeping a log of what you eat each day and the symptoms you have is very helpful. That way, you can link up things and have an accurate representation of what your symptoms really are. If you look around on this board, you'll find lots of helpful advice. Best of luck, and keep us updated. BackFire44