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This is kind of interesting. I was thinking of trying B12 because there are a lot of nerve endings in the anal passage and maybe B12 or some type of therapy which affects nerves would help. There was a study on rats on PubMed regarding this (http://www.ncbi.nlm.nih.gov/pubmed/8021696) and it said that the rats that improved were receiving 500mcg of B12 per kg of body weight. Most B12 seems to come in 1000 mcg doses, so this would involve taking maybe 30-40 caps, depending on body weight. I might get the 5000mcg tabs and see if they help.
 
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