I was on it for a while, and didn't really have much luck with a 50mg dose (3 per day) - so my doctor put me on a 100mg's (3 per day) and I found I have even more D then when I first started taking it. I'm on Zelnorm now - it's been oK so far.Everyone is different, you may want to give the Dicetel a go.Good luckSp.