I got my sample the day before yesterday and took two pills yesterday, one in the morning and one at night. When I went to bed I could feel a hardness in the left side of my colon, but it wasn't painful, just slightly full feeling. I did feel a little anxiety about it. I am an alternating C and D type and tend to feel anxiety at the first twinge in my colon. I was afraid to try taking too many at first (it says you can take 1-2 tablets 2-4 times a day), not knowing if it would cause me to cramp up. It's probably too early to report anything yet, but I did have a movement this morning that was pain-free and fairly smooth. I am hoping for normal stool formation. What I got was very soft thin stools with lumps within them. Rather unusual.I am going to finish the whole sample to see what happens.