I have been taking Zelnorm for about two years. I have suffered from ibsc for most of my life. I take Zelnorm 6mg plus one Milk of Magnesia tablet on a schedule: Tues.Thurs.Sat.Sun evenings. Always one hour before dinner. I am tied into the house on those nights as a result. My body's response to the med is unpredictable, causes diarreah, bloating, constant running into the bathroom for at least one to two hours, sometimes more. Sometimes all I get is urgency and bloating and no movement, which carries into discomfort on the following day. It affects my sleep, my well being, my psyche is battered as well as my gut. I am at the end of my rope. I will be seeing my gastro in another couple months, or I have the option of setting up an earlier appt. I don't know what options are leftfor me as far as managing this horrendous affliction. Anyone out there with a similar experience? How are you handling it?