Well, I am taking CREON, a pancreatic enzyme, 3 times a day with meals, and though it has not cured me, it has helped enormously. They were prescription from my doc, so if you're looking for an otc all-natural ibs cure you're out of luck, but I don't think they have any of serious side effects (definitely none for me) that many other ibs drugs have. Good luck! By the way, I have ibs-d, and I did not get these because of an abnormal test - my doc just thought they were worth a shot.
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