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Efficacy, Safety, and Tolerability in the treatment of Irritable Bowel Syndrome with DiarrheaDetails: The purpose of this study is to determine the efficacy, safety, and tolerability of different doses of JNJ-27018966 compared with placebo in the treatment of patients with irritable bowel syndrome with diarrhea (IBS-d).Ages Eligible for the Study: 18 - 65 yrs oldGenders Eligible for the Study: Male and FemalesContact Information:Allegiant Clinical ResearchAna Laura Gutierrez, [email protected] Dashwood suite 302Houston Tx. 77081P: 832-380-8180F: 713432-1283Principal Investigator: Alfredo Gueler MD.