I take 25 mg, in the morning (slow release capsule, so I don't get too tired and I find it more effective taken in the morning). I put on about 4 pounds quite rapidly but then I started looking at my diet a bit and now I'm stable. I do find doing sports extremely effective to control the the weight gain of this medication.I always used to eat sweets very moderately but I've also noticed that when I eat sweets now it's hard to stop. However, now that I'm aware of this as an effect of the amitryptilene I find eat easier to control the urge though it's easiest when I cut out sweets completely.... Altogether the amitryptilene (elavil) makes a huge difference, I feel much better.All the bestSusanne