I have had IBS D for 35 years. For the last several years I have had it mostly under control using immodium and calcium. I haven't exactly followed the calcium protocol you advocate. I take two Immodium with a caltrate plus D in the Am and the same at bedtime. For the most part this works. If I have an incident then I will take extra immodium immediately and a calcium at noon. Now my Dr. tells me I need to be on synthroid and I know I will have to take my calcium several hours after the synthroid, however I was also told that my calcium level was high. I am afraid to lower the amount of calcium I am taking, but I am also afraid to have an elevated calcium level. Have you ever heard of this and if so what do you suggest.