(Entero) Virus Related Muscle Damage Tied to Chronic Fatigue Syndrome

quote: Chronic fatigue syndrome seems to occur sometimes after a virus infection. Now, researchers have shown that some patients with the syndrome have evidence of virus in their muscles, and this in turn is linked to abnormal muscle function. ...Muscle biopsy samples from 10 of the 48 chronic fatigue patients were positive for enterovirus RNA. In addition, the patients with chronic fatigue syndrome went through an exercise test on the day of the biopsy, and the researchers measured the patients' blood levels of lactic acid before and after the test. Twenty-eight patients had an abnormal lactate response to exercise, "reflecting impaired muscle energy metabolism." Moreover, 9 of the 10 subjects who tested positive for the presence of virus in their muscles had this abnormal response. ...The team concludes that their findings support the notion that chronic fatigue syndrome has different causes, "and that some cases have a peripheral component to their fatigue related to muscle dysfunction."

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