I haven't been taking Citricel for long, but my Gastroenterologist recommended that I take it at least 2 times a day. He also told me to up my fiber intake with foods as well, and to drink 48 ounces of water a day. I hardly ever drink water, so this has been hard. This is on top of any juices, etc. Start slowly adding fiber, as it may make you have cramping. Good luck!!! Have you seen a Dr. yet? Everyone is different, and I may never be able to get up to the amt. of fiber he wants me to which is 45 grams per day. That is quite a lot. Just add it slowly.