I use it regularly in a combo supplement for cholesterol control. While I didn't begin this until after I got my D under good control with the flavonoids I also use for cholesterol anti-oxidation, I will say that during periods when I stopped taking the flavonoids but continued with the omega 3s, the D did come back. For me, I don't think it's anti-inflammatory benefits are enough and certainly are no match for the flavonoids.Mark