I have suffered from IBS for the past 20 years. The ONLY thing that helped me was Lotronex! I have seen on this web site advertising of Ibsacol and Bowel Soothe. I was wondering if this has worked for anyone. I am not very trusting of these things because they all seem to be gimmicks and never help me. I have tried the calcium pills and that just makes my symptoms worse. I used my last Lotronex pill about a month ago and I am trying to find some type of relief, if there is anything out there. I would appreciate any advice....THANKS