I started a post about IBS or Leaky Gut on Oct. 26th. I had started taking Grapefruit Seed Extract capsules on Oct. 9th. I can now say for sure, after 1 month and 1 week later, that I consider myself cured!! I have even had to start eating refried beans, navy beans and northern beans at least once a day to keep from getting constipated. I had IBS-d for 20 years. I quit taking the grapefruit seed capsules after 3 weeks. I may take one a week just for maintenance purposes. The grapefruit seed extract is supposed to kill off the yeast build up in our colon or bad bacteria in our colon. I've been taking a probiotic capsule every day now. I have not tried tyramines yet just because I'm so scared of another migraine. But... I have not had a migraine for quite sometime. I think once I can start eating all foods again my constipation should ease up. I really believe there is something to IBS being yeast or bad bacteria in our bodies that we just need to get rid of.