I will be on Lotronex for a week now. Yesterday was not a good day for me. I took my Lotronex in the morning and I took a whole pill. Last evening around 8:00 I started getting these gas pains, which I have been getting and the next thing I knew I was in the bathroom with very loose stools. I just don't get it. One day I'm constipated and then I have these problems. I don't recall getting the gas pains the first time I took Lotronex a year ago. My stomach just hasn't been feeling right. I'm so use to taking Imodium. I know I have to give this time, but I'm just wondering if anyone else out there is experiencing this?