Hi,I have suffered with IBS (with constipation) for 6 years now. It came on pretty suddenly initially and has progressed. I am in pain almost 24 hours a day and by evening I look 6 months pregnant. Severe abdominal pain, gas, bloating etc. I have tried EVERYTHING. Diet, supplements, colonics. Been to 3 different GIs and had colonoscopies and other tests and nothing has been revealed. Last week my doctor put me on Xifaxan. 200mg 2x a day. So far the pain has subsided a bit. The bloating is still there, but the severe pain and some of the gas has been a bit better. Not perfect, but noticeably improved some. I wonder if any of you have tried Xifaxan before and what your experiences are.Take care!